Article
Alcohol dehydrogenase polymorphisms influence alcohol-elimination rates in a male Jewish population.
Alcoholism, clinical and experimental research - 1 Jan 2004
Neumark Yehuda D, Friedlander Yechiel, Durst Ronen, Leitersdorf Eran, Jaffe Dena, Ramchandani Vijay A, O'Connor Sean, Carr Lucinda G, Li T K
Abstract excerpt
BACKGROUND: Genetic variation in the alcohol dehydrogenase (ADH) enzyme is associated with an aversion to alcohol and a lower risk of alcoholism among Asians. There is growing evidence of a functional role of the ADH2*2 allele in alcohol-drinking patterns among Jews, who have traditionally exhibited low rates of alcoholism and alcohol-related problems. The mechanism by which this allelic effect is mediated is not...
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