Article
Back to the future with ubiquitin.
Cell - 23 Jan 2004
Pickart Cecile M
Abstract excerpt
Two papers published in 1984 by the Varshavsky laboratory revealed that the ubiquitin/proteasome pathway is the principal system for degradation of short-lived proteins in mammalian cells, setting the stage for future demonstrations of this pathway's many regulatory roles. This perspective discus...
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