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Article

Frequency distribution of antimalarial drug-resistant alleles among isolates of Plasmodium falciparum in Purworejo district, Central Java Province, Indonesia.

The American journal of tropical medicine and hygiene - 1 Dec 2003

Syafruddin D, Asih Puji B S, Aggarwal Sona L, Shankar Anuraj H

Abstract excerpt

Treatment failures to the first- and second-lines antimalarial drugs chloroquine and sulfadoxine-pyrimethamine have increased in the Purworejo district on the island of Java, Indonesia. A molecular epidemiologic study was conducted to determine the frequency distribution of mutant alleles of the genes associated with the resistance among the isolates of Plasmodium falciparum from the area. Analyses using a...

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PMID: 14740877

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