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Article

The low evolutionary rate of human T-cell lymphotropic virus type-1 confirmed by analysis of vertical transmission chains.

Molecular biology and evolution - 1 Mar 2004

Van Dooren S, Pybus O G, Salemi M, Liu H-F, Goubau P, Remondegui C, Talarmin A, Gotuzzo E, Alcantara L C J, Galvão-Castro B, Vandamme A-M

Abstract excerpt

The evolutionary rate of the human T-cell lymphotropic virus type-1 (HTLV-1) is considered to be very low, in strong contrast to the related human retrovirus HIV. However, current estimates of the HTLV-1 rate rely on the anthropological calibration of phylogenies using assumed dates of human migration events. To obtain an independent rate estimate, we analyzed two variable regions of the HTLV-1 genome (LTR and...

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PMID: 14739252
DOI: 10.1093/molbev/msh053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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