The time of palatal fusion in mice: a factor of strain susceptibility to teratogens.

Abstract excerpt

Induction of facial clefts in an animal model is often performed in experimental teratology. The susceptibility to teratogens of different strains of mice is genetically determined and seems to depend on the time of palatal fusion during embryogenesis. In order to elucidate the mode of action of preventive measures, we determined the exact time of palatal fusion in different strains of mice used for experiments...

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