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Article

MtDNA evidence for a genetic bottleneck in the early history of the Ashkenazi Jewish population.

European journal of human genetics : EJHG - 1 May 2004

Behar Doron M, Hammer Michael F, Garrigan Daniel, Villems Richard, Bonne-Tamir Batsheva, Richards Martin, Gurwitz David, Rosengarten Dror, Kaplan Matthew, Della Pergola Sergio, Quintana-Murci Lluis, Skorecki Karl

Abstract excerpt

The relative roles of natural selection and accentuated genetic drift as explanations for the high frequency of more than 20 Ashkenazi Jewish disease alleles remain controversial. To test for the effects of a maternal bottleneck on the Ashkenazi Jewish population, we performed an extensive analysis of mitochondrial DNA (mtDNA) hypervariable segment 1 (HVS-1) sequence and restriction site polymorphisms in 565...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 14722586
DOI: 10.1038/sj.ejhg.5201156

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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