Article
Molecular isoforms of murine CD44 and evidence that the membrane proximal domain is not critical for hyaluronate recognition.
The Journal of cell biology - 1 Dec 1992
He Q, Lesley J, Hyman R, Ishihara K, Kincade P W
Abstract excerpt
We previously found that the CD44 glycoprotein on some lymphocytes can mediate adhesion to hyaluronate (HA) bearing cells. However, many questions remain about the molecular heterogeneity of CD44 and mechanisms which control its recognition of this ligand. In vitro mutagenesis and DNA sequencing have now been used to investigate the importance of the membrane proximal region of murine CD44 for recognition of...
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