Article
SETH1 and SETH2, two components of the glycosylphosphatidylinositol anchor biosynthetic pathway, are required for pollen germination and tube growth in Arabidopsis.
The Plant cell - 1 Jan 2004
Lalanne Eric, Honys David, Johnson Andrew, Borner Georg H H, Lilley Kathryn S, Dupree Paul, Grossniklaus Ueli, Twell David
Abstract excerpt
Glycosylphosphatidylinositol (GPI) anchoring provides an alternative to transmembrane domains for anchoring proteins to the cell surface in eukaryotes. GPI anchors are synthesized in the endoplasmic reticulum via the sequential addition of monosaccharides, fatty acids, and phosphoethanolamines to phosphatidylinositol. Deficiencies in GPI biosynthesis lead to embryonic lethality in animals and to conditional...
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