Article
[Genetic determinants of hereditary thrombophilia in pathogenesis of venous thrombosis].
Terapevticheskii arkhiv - 1 Jan 2003
Kapustin S I, Blinov M N, Kargin V D, Filanovskaia L I, Saltykova N B, Beliazo O E, Golovina O G, Shmeleva V M, Panshina A M, Papaian L P
Abstract excerpt
AIM: To study the role of genetic determinants of hereditary thrombophilia in pathogenesis of various clinical manifestations of venous thrombosis in the citizens of the North-West Region of Russia. MATERIAL AND METHODS: Mutations of the genes of factor V (FV Leiden), prothrombin (G20210-A) and polymorphism C677-T in the gene of methylentetrahydrofolate reductase (MTHFR) were detected using polymerase chain...
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