Article
Expression of the Arp11 gene suppresses the tumorigenicity of PC-14 human lung adenocarcinoma cells.
Biochemical and biophysical research communications - 26 Dec 2003
Shindo-Okada Nobuko, Iigo Masaaki
Abstract excerpt
We recently reported the isolation of a novel actin-related gene, Arp11, from a PC-14 human lung adenocarcinoma clone with low metastatic and tumorigenic ability. In this paper, we report the effect of Arp11 expression on PC-14 tumor growth. We transfected a highly metastatic and tumorigenic PC-14 line, Lu-2, with an Arp11 expression vector, and obtained five stable transfectants that each express Arp11 at...
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