Article
The C(-260)>T gene polymorphism in the promoter of the CD14 monocyte receptor gene is not associated with acute myocardial infarction.
Clinical and experimental medicine - 1 Nov 2003
Longobardo M T, Cefalù A B, Pezzino F, Noto D, Emmanuele G, Barbagallo C M, Fiore B, Monastero R, Castello A, Molini V, Notarbartolo A, Travali S, Averna M R
Abstract excerpt
CD surface molecules mediates cell activation and signaling. In particular, CD14 on blood monocytes mediate monocyte/macrophage activation by lipopolysaccharide. Lipopolysaccharide and its receptor, CD14, have been implicated in atherogenesis. It has been recently shown that a C(-260)T polymorphism in the promoter of the CD14 receptor may be a risk factor for coronary artery disease. Recently this association has...
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