Article
High deleterious genomic mutation rate in stationary phase of Escherichia coli.
Science (New York, N.Y.) - 28 Nov 2003
Loewe Laurence, Textor Volker, Scherer Siegfried
Abstract excerpt
In natural habitats, bacteria spend most of their time in some form of growth arrest. Little is known about deleterious mutations in such stages, and consequently there is limited understanding of what evolutionary events occur. In a deleterious mutation accumulation experiment in prolonged stationary phase of Escherichia coli, about 0.03 slightly deleterious mutations were observed per genome per day. This is...
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