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Article

Modulation of HDL metabolism by probucol in complete cholesteryl ester transfer protein deficiency.

Atherosclerosis - 1 Nov 2003

Noto Hiroshi, Kawamura Mitsunobu, Hashimoto Yoshiaki, Satoh Hiroaki, Hara Masumi, Iso-o Naoyuki, Togo Masako, Kimura Satoshi, Tsukamoto Kazuhisa

Abstract excerpt

Probucol, an antioxidative and hypolipidemic agent, has been postulated to increase reverse cholesterol transport by enhancing cholesteryl ester transfer protein (CETP) activity. However, its clinical implication in CETP deficient patients has not been fully defined. To characterize the effects of probucol in the absence of CETP, we evaluated the changes in lipid profile, lipid peroxidation, and paraoxonase 1...

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Source

Identifiers

PMID: 14642415
DOI: 10.1016/j.atherosclerosis.2003.08.005

Genes

CETP
PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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