Article
Genome mosaicism is conserved but not unique in Pseudomonas aeruginosa isolates from the airways of young children with cystic fibrosis.
Environmental microbiology - 1 Dec 2003
Ernst Robert K, D'Argenio David A, Ichikawa Jeffrey K, Bangera M Gita, Selgrade Sara, Burns Jane L, Hiatt Peter, McCoy Karen, Brittnacher Mitchell, Kas Arnold, Spencer David H, Olson Maynard V, Ramsey Bonnie W, Lory Stephen, Miller Samuel I
Abstract excerpt
Pseudomonas aeruginosa strains from the chronic lung infections of cystic fibrosis (CF) patients are phenotypically and genotypically diverse. Using strain PAO1 whole genome DNA microarrays, we assessed the genomic variation in P. aeruginosa strains isolated from young children with CF (6 months to 8 years of age) as well as from the environment. Eighty-nine to 97% of the PAO1 open reading frames were detected in...
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