Genetic features of mitochondrial respiratory chain disorders.

Abstract excerpt

Oxidative phosphorylation, i.e., ATP synthesis by the oxygen-consuming respiratory chain (RC), supplies most organs and tissues with a readily usable energy source, being functional before birth. Consequently, RC deficiencies can theoretically give rise to any symptom, in any organ or tissue, at any age and with any mode of inheritance, because of the twofold genetic origin of RC components (nuclear DNA and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to DNA, Mitochondrial
• Share to Mitochondria
• Share to Mitochondrial Diseases