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Article

KKL-35 inhibits growth of Staphylococcus aureus by systematically changing bacterial phenotypes.

Archives of microbiology - 12 Jul 2024

Xu Jie, Wei Zilan, Fang Wendong, Wu Jiahui, Wang Youliang, Chen Shuiping

Abstract excerpt

KKL-35 is a new oxadiazole compound with potent broad-spectrum antibacterial activity against a number of gram-positive and gram-negative bacteria. However, its influences on bacterial growth are unclear. This study is to investigate phenotypic changes of Staphylococcus aureus (SA) caused by KKL-35 and evaluate antibacterial activity of combinations of KKL-35 with 7 class of antibiotics available in medical...

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PMID: 38995446
DOI: 10.1007/s00203-024-04079-0

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