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Article

SLC40A1 Q248H allele frequencies and Q248H-associated risk of non-HFE iron overload in persons of sub-Saharan African descent.

Blood cells, molecules & diseases - 1 Jan 2000

Barton James C, Acton Ronald T, Lee Pauline L, West Carol

Abstract excerpt

The ferroportin polymorphism SLC40A1 Q248H (exon 6, cDNA 744G-->T; Gln248His) occurs in persons of sub-Saharan African descent with and without iron overload, and is associated with elevated serum ferritin concentrations (SF). However, the risk of iron overload associated with Q248H has not been defined. We tabulated previously reported Q248H allele frequency estimates in African-Americans and Native Africans,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17490902
DOI: 10.1016/j.bcmd.2007.03.008
PMCID: PMC1986732

Genes

HFE

Variants

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