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Article

Diverse range of fixed positional deformities and bone growth restraint provoked by flaccid paralysis in embryonic chicks

1 Aug 2003

Abstract excerpt

Pancuronium bromide (PB) is used in neonates and pregnant women to induce limp, flaccid paralysis in order to allow mechanical ventilation during intensive care. Such non-depolarizing neuromuscular blocking drugs are administered to 0.1% of all human births in the UK. In this study, we examined PB effects on skeletal development in chick embryos. PB treatment produced skeletal deformities associated with...

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PMID: 14632633
DOI: 10.1046/j.1365-2613.2003.00353.x

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