Host strain, H-2 genotype and immunocompetence do not affect the survival or development of Onchocerca lienalis infective larvae implanted within micropore chambers into mice or rats.

doi:10.1017/s003118200007462x

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Article

Host strain, H-2 genotype and immunocompetence do not affect the survival or development of Onchocerca lienalis infective larvae implanted within micropore chambers into mice or rats.

Parasitology - 1 Dec 1992

Taylor M J, Van Es R P, Townson S, Bianco A E

Abstract excerpt

The survival, growth and development of Onchocerca lienalis 3rd-stage (L3) larvae implanted into mice within micropore chambers has been studied with a view to developing a vaccination model for studies of protective immunity in onchocerciasis. The influence of host genetics on worm recoveries and development (growth and moulting rate) was analysed in a panel of inbred mice (CBA, BALB/c, DBA/2, SJL, 129J,...

Topics

Animals
Diffusion Chambers, Culture
Disease Models, Animal
Disease Susceptibility
Genotype
Immunity, Cellular
Immunocompetence
Immunocompromised Host
Larva
Leukocyte Count
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Inbred Strains

Mice, SCID

Onchocerca

Onchocerciasis

Phagocytosis

Rats

Source

Open in PubMed

Identifiers

PMID: 1461685
DOI: 10.1017/s003118200007462x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1461685-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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