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Article

Association of a polymorphism of the dopamine receptor D4 gene with bone mineral density in Japanese men.

Journal of human genetics - 1 Jan 2003

Yamada Yoshiji, Ando Fujiko, Niino Naoakira, Shimokata Hiroshi

Abstract excerpt

A -521C-->T polymorphism in the promoter of the dopamine receptor D4 gene (DRD4) has been associated with novelty-seeking behavior in Japanese. Given that the dopaminergic system might also play an important role in bone metabolism, the relation of the -521C-->T polymorphism of DRD4 to bone mineral density (BMD) was examined in 2,228 Japanese subjects (1,123 men; 1,105 women) who were randomly recruited to a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14605948
DOI: 10.1007/s10038-003-0090-7

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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