Article
Microarrays for genotyping human group a rotavirus by multiplex capture and type-specific primer extension.
Journal of clinical microbiology - 1 Nov 2003
Lovmar Lovisa, Fock Caroline, Espinoza Felix, Bucardo Filemon, Syvänen Ann-Christine, Bondeson Kåre
Abstract excerpt
Human group A rotavirus (HRV) is the major cause of severe gastroenteritis in infants worldwide. HRV shares the feature of a high degree of genetic diversity with many other RNA viruses, and therefore, genotyping of this organism is more complicated than genotyping of more stable DNA viruses. We describe a novel microarray-based method that allows high-throughput genotyping of RNA viruses with a high degree of...
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