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Article

Human interferon consensus sequence binding protein is a negative regulator of enhancer elements common to interferon-inducible genes.

1 Dec 1992

Abstract excerpt

The promoter regions of many interferon-inducible genes share a short DNA sequence motif, termed the interferon consensus sequence (ICS) to which several regulatory proteins bind. A murine cDNA which encodes an ICS binding protein has been reported (M-ICSBP). The cloning of the human homologue of ICSBP (H-ICSBP) is described. H-ICSBP shares high sequence homology with its murine cognate. The derived sequence of...

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Identifiers

PMID: 1460054
DOI: 10.1016/s0021-9258(19)74081-2

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