Article
Oxyphilic and non-oxyphilic thyroid carcinoma cell lines differ in expressing apoptosis-related genes.
Journal of endocrinological investigation - 1 Jul 2003
Allìa E, Cassoni P, Marrocco T, Volante M, Bussolati B, Wong M, Clark O H, Papotti M
Abstract excerpt
Oxyphilic tumors of the thyroid are characterized by mitochondrion-rich cells and extensive DNA fragmentation. In order to clarify if a different expression of apoptosis-related genes could be responsible for DNA fragmentation in oxyphilic cell tumors, two thyroid follicular carcinoma-derived cell lines, having oxyphilic (XTC.UC1) and non-oxyphilic (WRO) features, were compared applying a gene array technique....
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