Article
Genetic study of orosomucoid by isoelectric focusing and immunoprinting in patients with carcinoma.
Electrophoresis - 1 Jan 2000
Mittermüller J, Weidinger S
Abstract excerpt
The carbohydrate moiety of the orosomucoid (ORM) molecule shows microheterogeneity [1] and the pteridine-containing variant seems to be tumor-specific [2-4]. However, there also exists a genetic (protein-related) polymorphism coded by the ORM1 and ORM2 loci on chromosome 9 [5, 6]. To investigate the relationship between ORM1 gene products and the development of carcinoma, we analyzed the ORM1 phenotypes of...
Topics
- Alleles
- Antibodies
- Female
- Gene Frequency
- Humans
- Isoelectric Focusing
- Male
- Neoplasms
- Orosomucoid
- Phenotype
- Polymorphism, Genetic
