Article
Targeted mutation of a Drosophila odor receptor defines receptor requirement in a novel class of sensillum.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 29 Oct 2003
Elmore Tamara, Ignell Rickard, Carlson John R, Smith Dean P
Abstract excerpt
In vertebrates, individual olfactory neurons are thought to express a single odorant receptor (Or) gene, but it is not clear that all odor-evoked activity in each neuron is exclusively dependent on an individual odorant receptor. In Drosophila, little is known about what receptors impart odor sensitivity to particular olfactory neurons. Here, we demonstrate the use of gene targeting to produce a null mutant of...
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