Article
Cancer prone persons. A randomized screening trial based on colonoscopy: background, design and recruitment.
Familial cancer - 1 Jan 2001
Eisinger F, Giordanella J P, Brigand A, Didelot R, Jacques D, Schenowitz G, Julian-Reynier C, Seitz J F, Sobol H, Faivre J, Allemand H
Abstract excerpt
OBJECTIVE: Evidence-based counseling and prevention are not available so far for hereditary cancer prone persons, since we lack data based on clinical trials. There are very few high-risk persons in the population as a whole. Based on a familial history analysis, only 1.2% of all healthy volunteers attending screening centers reached the arbitrary high-risk level defined as a Relative Risk of more than 4. We...
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