Article
Complex segregation analysis of 1,792 cleft lip and palate families in South America: 1967-1997.
Pesquisa odontologica brasileira = Brazilian oral research - 1 Jan 2000
Vieira Alexandre Rezende, Romitti Paul Anthony, Orioli Iêda Maria, Castilla Eduardo Enrique
Abstract excerpt
Although several studies have demonstrated familial aggregation of nonsyndromic cleft lip with or without cleft palate (CL/P), its model of inheritance remains uncertain. We report the results of complex segregation analysis performed in South American families with a newborn affected with CL/P. Families of 1,792 consecutive newborns affected with CL/P and registered during the period 1967 to 1997 were studied. A...
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