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Article

Hyperdopaminergic mutant mice have higher "wanting" but not "liking" for sweet rewards.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Oct 2003

Peciña Susana, Cagniard Barbara, Berridge Kent C, Aldridge J Wayne, Zhuang Xiaoxi

Abstract excerpt

What is the role of dopamine in natural rewards? A genetic mutant approach was taken to examine the consequences of elevated synaptic dopamine on (1) spontaneous food and water intake, (2) incentive motivation and learning to obtain a palatable sweet reward in a runway task, and (3) affective "liking" reactions elicited by the taste of sucrose. A dopamine transporter (DAT) knockdown mutation that preserves only...

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PMID: 14561867
PMCID: PMC6740586

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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