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Article

Phenylbutyrate increases SMN expression in vitro: relevance for treatment of spinal muscular atrophy

15 Oct 2003

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Share to Congenital Anomalies and Fetal Surgery
Share to Neurogenetic and Muscular Disorders Research
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Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 14560316
DOI: 10.1038/sj.ejhg.5201102

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Related research

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Phenylbutyrate increases SMN expression in vitro: relevance for treatment of spinal muscular atrophyPMID 14560316Read ↗

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Salbutamol increases SMN mRNA and protein levels in spinal muscular atrophy cellsSemantic proximity Read ↗

Longitudinal evaluation of SMN levels as biomarker for spinal muscular atrophy: results of a phase IIb double-blind study of salbutamolSemantic proximity Read ↗

LBH589 induces up to 10-fold SMN protein levels by several independent mechanisms and is effective even in cells from SMA patients non-responsive to valproateSemantic proximity Read ↗

Effect of the Butyrate Prodrug Pivaloyloxymethyl Butyrate (AN9) on a Mouse Model for Spinal Muscular Atrophy.Semantic proximity Read ↗

Discovery, Synthesis, and Biological Evaluation of Novel SMN Protein ModulatorsSemantic proximity Read ↗

Diverse small-molecule modulators of SMN expression found by high-throughput compound screening: early leads towards a therapeutic for spinal muscular atrophySemantic proximity Read ↗

Valproic acid increases SMN levels in spinal muscular atrophy patient cellsSemantic proximity Read ↗

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