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Article

Comprehensive evaluation of the association between prostate cancer and genotypes/haplotypes in CYP17A1, CYP3A4, and SRD5A2.

European journal of human genetics : EJHG - 1 Apr 2004

Loukola Anu, Chadha Monica, Penn Sharron G, Rank David, Conti David V, Thompson Deborah, Cicek Mine, Love Brad, Bivolarevic Vesna, Yang Qiner, Jiang Yalin, Hanzel David K, Dains Katherine, Paris Pamela L, Casey Graham, Witte John S

Abstract excerpt

Genes involved in the testosterone biosynthetic pathway - such as CYP17A1, CYP3A4, and SRD5A2 - represent strong candidates for affecting prostate cancer. Previous work has detected associations between individual variants in these three genes and prostate cancer risk and aggressiveness. To more comprehensively evaluate CYP17A1, CYP3A4, and SRD5A2, we undertook a two-phase study of the relationship between their...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 14560315
DOI: 10.1038/sj.ejhg.5201101

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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