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Article

Encoding of a Homolog of the IFN-γ Receptor by Myxoma Virus

20 Nov 1992

Abstract excerpt

Many poxvirus-encoded virulence factors have been identified as proteins that are secreted from infected cells. The major secreted protein (37 kilodaltons) from cells infected with myxoma virus is encoded by the M-T7 open reading frame. This protein has significant sequence similarity to the human and mouse receptors for interferon-gamma (IFN-gamma). Furthermore, the myxoma M-T7 protein specifically binds rabbit...

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PMID: 1455233
DOI: 10.1126/science.1455233

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