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Article

Covariation of backbone motion throughout a small protein domain.

Nature structural biology - 1 Nov 2003

Mayer Kristen L, Earley Matthew R, Gupta Sonia, Pichumani Kumar, Regan Lynne, Stone Martin J

Abstract excerpt

The synchronization (correlation) of conformational fluctuations in folded proteins may influence the rates of enzyme catalysis and ligand binding as well as the stabilities of native proteins and their complexes. However, experimental detection of correlated motions remains difficult. Herein, we...

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PMID: 14528292
DOI: 10.1038/nsb991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-14528292-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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