Article
Geographical clusters of dengue virus type 2 isolates based on analysis of infected cell RNA by the chemical cleavage at mismatch method.
Journal of virological methods - 1 Nov 1992
Lin B, Cotton R G, Trent D W, Wright P J
Abstract excerpt
Genetic variation in 12 strains of dengue virus type 2, isolated from several epidemic areas in different years, was studied by chemical cleavage at mismatched cytosine in DNA:RNA heteroduplexes. End-labelled cDNA probes derived from the E and NS2A genes of the New Guinea C strain were hybridized...
Topics
- Base Composition
- Cytosine
- DNA
- DNA Probes
- Dengue Virus
- Genes, Viral
- Genetic Variation
- Hydroxylamine
- Hydroxylamines
- Nucleic Acid Heteroduplexes
- RNA, Viral
- Viral Envelope Proteins
