Article
Redefining the role of psr in beta-lactam resistance and cell autolysis of Enterococcus hirae.
Journal of bacteriology - 1 Oct 2003
Sapunaric Frédéric, Franssen Christine, Stefanic Patrick, Amoroso Ana, Dardenne Olivier, Coyette Jacques
Abstract excerpt
The contribution of penicillin-binding protein 5 (PBP5) and the PBP5 synthesis repressor (Psr) to the beta-lactam resistance, growth, and cell autolysis of wild-type strain ATCC 9790 and resistant strain R40 of Enterococcus hirae was investigated by disruption or substitution of the corresponding pbp5 and psr genes by Campbell-type recombination. The resulting modifications were confirmed by hybridization and...
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