Article
Generation and characterization of a monoclonal antibody specific for human herpesvirus 6 variant A immediate-early 2 protein.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Dec 2003
Arsenault Suzie, Gravel Annie, Gosselin Jean, Flamand Louis
Abstract excerpt
Two variants (A and B) of human herpesvirus 6 (HHV-6) can be isolated from humans, with each variant having unique biological properties. HHV-6 variant typing is mainly done following amplification of viral genomic DNA followed by restriction endonuclease digestion. Our objective was to generate a monoclonal antibody (mAb) that would allow us to discriminate between variants A and B of HHV-6. BALB/c mice were...
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