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Article

Polymorphisms in XRCC1 and glutathione S-transferase genes and hepatitis B-related hepatocellular carcinoma.

Journal of the National Cancer Institute - 1 Oct 2003

Yu Ming-Whei, Yang Shi-Yi, Pan I-Jen, Lin Chih-Lin, Liu Chun-Jen, Liaw Yun-Fan, Lin Shi-Ming, Chen Pei-Jer, Lee Shou-Dong, Chen Chien-Jen

Abstract excerpt

Chronic infection with hepatitis B virus (HBV) causes DNA damage. An arginine (Arg)-to-glutamine (Gln) polymorphism at codon 399 in the XRCC1 gene is putatively associated with DNA damage. In a case-control study of 577 HBV surface antigen carriers with hepatocellular carcinoma (HCC) and 389 HBV...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to X-ray Repair Cross Complementing Protein 1

Source

Identifiers

PMID: 14519756
DOI: 10.1093/jnci/djg051

Genes

XRCC1
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14519756-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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