Article
Polycystic ovary syndrome: syndrome XX?
Trends in endocrinology and metabolism: TEM - 1 Oct 2003
Sam Susan, Dunaif Andrea
Abstract excerpt
Polycystic ovary syndrome (PCOS) is now recognized as an important metabolic and reproductive disorder. It is associated with substantial defects in insulin action and secretion that confer a markedly increased risk for type 2 diabetes mellitus. Insulin resistance modifies reproductive function both by the direct actions of insulin on steroidogenesis and by disruption of insulin signaling pathways in the central...
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