Article
Association between HLA class I antigens and response to interferon therapy in children with chronic HBV hepatitis.
Archives of virology. Supplementum - 1 Jan 1992
Giacchino R, Nocera A, Timitilli A, Cristina E, Giambartolomei G, Caocci F, Cirillo C, Barocci S
Abstract excerpt
In this preliminary study, children with chronic HBV hepatitis, as was also previously shown for adults, respond to interferon therapy in an HLA class I antigen dependent manner. If this can be confirmed on a large scale, HLA typing may serve as a useful indication of interferon-therapy responders.
Topics
- Alleles
- Child
- Genes, MHC Class I
- HLA-B35 Antigen
- Hepatitis B
- Hepatitis, Chronic
- Humans
- Interferon-alpha
