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Article

Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).

Antimicrobial agents and chemotherapy - 1 Oct 2003

Nash Kevin A

Abstract excerpt

High-level, acquired macrolide resistance in mycobacteria is conferred by mutation within the 23S rRNA gene. However, several mycobacteria are naturally resistant to macrolides, including the Mycobacterium smegmatis group and Mycobacterium tuberculosis complex. Thus, the aim of this study was to characterize this resistance. Intrinsic macrolide resistance in M. smegmatis was inducible and showed cross-resistance...

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Share to Clarithromycin
Share to Drug Resistance, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

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Share to RNA, Ribosomal, 23S

Share to tRNA Methyltransferases

Source

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Identifiers

PMID: 14506008
DOI: 10.1128/AAC.47.10.3053-3060.2003
PMCID: PMC201133

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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