Article
Three human osteosarcoma cell lines exhibiting different phenotypic expressions.
Acta pathologica japonica - 1 Aug 1992
Hotta T, Motoyama T, Watanabe H
Abstract excerpt
to elucidate the differences in histological features and biological behavior of osteosarcomas, three human osteoblastic-type osteosarcomas were studied in vitro and in nude mice. The secretory processing and extracellular fiber formation of type I collagen proved to be the most important factor...
Topics
- Alkaline Phosphatase
- Cell Division
- Collagen
- Humans
- Microscopy, Electron
- Neoplasm Transplantation
- Osteocalcin
- Osteosarcoma
- Phenotype
- Tumor Cells, Cultured
