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Article

Three human osteosarcoma cell lines exhibiting different phenotypic expressions.

Acta pathologica japonica - 1 Aug 1992

Hotta T, Motoyama T, Watanabe H

Abstract excerpt

to elucidate the differences in histological features and biological behavior of osteosarcomas, three human osteoblastic-type osteosarcomas were studied in vitro and in nude mice. The secretory processing and extracellular fiber formation of type I collagen proved to be the most important factor in bone formation in the osteosarcomas. Alkaline phosphatase also seemed to be important. However, we were unable to...

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Identifiers

PMID: 1449054
DOI: 10.1111/j.1440-1827.1992.tb03110.x

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