Article
Distribution of HLA-DQA1, -DQB1 and DRB1 alleles in black IDDM patients and controls from Zimbabwe.
Tissue antigens - 1 Sept 1992
Garcia-Pacheco J M, Herbut B, Cutbush S, Hitman G A, Zhonglin W, Magzoub M, Bottazzo G F, Kiere C, West G, Mvere D
Abstract excerpt
We have used the XI Histocompatibility Workshop sequence-specific oligonucleotide probes to determine the DRB1, DQA1 and DQB1 genotypes by dot-blot hybridization of polymerase chain reaction (pcr)-amplified material from a homogenous black population in Zimbabwe. The DR4 subtype DRB1*0405, the DR3 subtype DRB1*0301, DQB1*0201 and DQB1*0302 and DQA1*0301 and DQA1*0501 were significantly increased in the IDDM group...
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