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Article

Gene activity and cleavage arrest in human pre-embryos

1 Aug 1992

Abstract excerpt

There is a high rate of spontaneous cleavage arrest around the four- to eight-cell stage of human development in vitro. Since this coincides with the time of activation of the embryonic genome it has been suggested that cleavage arrest may occur as a consequence of failure of gene activation. Gene expression in human pre-embryos is associated with an alpha-amanitin sensitive, qualitative change in protein...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1430119
DOI: 10.1093/oxfordjournals.humrep.a137761

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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