Article
Length and sequence variation in the apolipoprotein B intron 20 Alu repeat.
Genomics - 1 Oct 1992
Shriver M D, Siest G, Boerwinkle E
Abstract excerpt
We have developed a single-stranded conformation polymorphism (SSCP) protocol for typing both sequence and length variations in an Alu element located in intron 20 of the human apolipoprotein B (apo B) gene. Using the polymerase chain reaction (PCR), we simultaneously amplified and isotopically labeled the apo B intron 20 Alu. The Alu tail, which is composed of two arrays of variable numbers of tandem repeats,...
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