Length and sequence variation in the apolipoprotein B intron 20 Alu repeat.

doi:10.1016/s0888-7543(05)80240-x

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Article

Length and sequence variation in the apolipoprotein B intron 20 Alu repeat.

Genomics - 1 Oct 1992

Shriver M D, Siest G, Boerwinkle E

Abstract excerpt

We have developed a single-stranded conformation polymorphism (SSCP) protocol for typing both sequence and length variations in an Alu element located in intron 20 of the human apolipoprotein B (apo B) gene. Using the polymerase chain reaction (PCR), we simultaneously amplified and isotopically l...

Topics

Alleles
Apolipoproteins
Base Sequence
Biological Evolution
DNA
Genetic Variation
Haplotypes
Heterozygote
Humans
Introns
Molecular Sequence Data
Pedigree
Polymerase Chain Reaction
Repetitive Sequences, Nucleic Acid

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