Article
Schistosoma mansoni: control of hepatotoxicity and egg excretion by immune serum in infected immunosuppressed mice is schistosome species-specific, but not S. mansoni strain-specific.
Experimental parasitology - 1 Nov 1992
Murare H M, Dunne D W, Bain J, Doenhoff M J
Abstract excerpt
Immunosuppressed mice infected with Schistosoma mansoni suffer from an acute hepatotoxicity reaction, and they fail to excrete as many parasite eggs as comparably infected immunologically intact control animals. The hepatotoxicity was shown here to be preventable, and egg excretion rates were enh...
Topics
- Animals
- Antigens, Helminth
- Cross Reactions
- Egg Proteins
- Genetic Variation
- Immune Sera
- Immunosuppression Therapy
- Immunotherapy, Adoptive
- Liver
- Mice
- Mice, Inbred CBA
- Ovum
- Schistosomiasis mansoni
- Species Specificity