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Article

[Morphofunctional aspects of genetic analysis of osteogenesis imperfecta in cultured skin fibroblasts].

Biulleten' eksperimental'noi biologii i meditsiny - 1 Jul 1992

Meerson E M, Barer F S, Berezhnyĭ A P, Prokhorova E V, Maliavko T P, Chernysheva E V, Neustroeva E P

Abstract excerpt

Osteogenesis imperfecta (OI) is a disease with biochemical evidence of abnormality in collagen biosynthesis. We report here that expression of the OI phenotype extends to the level of dermal fibroblast morphology in vitro. Growth characteristics and morphology of control (n = 3) and 01 cell strains (n = 10) were compared. Our results show that (1) OI fibroblasts take longer time (16 days) than that with control...

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PMID: 1421323

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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