[Morphofunctional aspects of genetic analysis of osteogenesis imperfecta in cultured skin fibroblasts].

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Article

[Morphofunctional aspects of genetic analysis of osteogenesis imperfecta in cultured skin fibroblasts].

Biulleten' eksperimental'noi biologii i meditsiny - 1 Jul 1992

Meerson E M, Barer F S, Berezhnyĭ A P, Prokhorova E V, Maliavko T P, Chernysheva E V, Neustroeva E P

Abstract excerpt

Osteogenesis imperfecta (OI) is a disease with biochemical evidence of abnormality in collagen biosynthesis. We report here that expression of the OI phenotype extends to the level of dermal fibroblast morphology in vitro. Growth characteristics and morphology of control (n = 3) and 01 cell strai...

Topics

Adolescent
Adult
Cells, Cultured
Child
Child, Preschool
Collagen
Cytoplasm
Fibroblasts
Fibronectins
Humans
Infant
Middle Aged
Osteogenesis Imperfecta
Phenotype
Skin

Source

Open in PubMed

Identifiers

PMID: 1421323

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1421323-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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