DNA diversity among clinical isolates of Helicobacter pylori detected by PCR-based RAPD fingerprinting.

doi:10.1093/nar/20.19.5137

Back to search

Article

DNA diversity among clinical isolates of Helicobacter pylori detected by PCR-based RAPD fingerprinting.

Nucleic acids research - 11 Oct 1992

Akopyanz N, Bukanov N O, Westblom T U, Kresovich S, Berg D E

Abstract excerpt

The RAPD (or AP-PCR) DNA fingerprinting method was used to distinguish among clinical isolates of Helicobacter pylori, a bacterium whose long term carriage is associated with gastritis, peptic ulcers and gastric carcinomas. This method uses arbitrarily chosen oligonucleotides to prime DNA synthes...

Topics

Animals
Base Sequence
DNA Fingerprinting
DNA, Bacterial
Genetic Variation
Helicobacter pylori
Humans
Molecular Sequence Data
Oligodeoxyribonucleotides
Polymerase Chain Reaction
Rats
Sequence Homology, Nucleic Acid

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.