Article
Repeat-associated plasticity in the Helicobacter pylori RD gene family.
Journal of bacteriology - 1 Nov 2009
Shak Joshua R, Dick Jonathan J, Meinersmann Richard J, Perez-Perez Guillermo I, Blaser Martin J
Abstract excerpt
The bacterium Helicobacter pylori is remarkable for its ability to persist in the human stomach for decades without provoking sterilizing immunity. Since repetitive DNA can facilitate adaptive genomic flexibility via increased recombination, insertion, and deletion, we searched the genomes of two H. pylori strains for nucleotide repeats. We discovered a family of genes with extensive repetitive DNA that we have...
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