Article
Familial amyloidosis: a study of 52 North American-born patients examined during a 30-year period.
Mayo Clinic proceedings - 1 May 1992
Gertz M A, Kyle R A, Thibodeau S N
Abstract excerpt
Between 1961 and 1990, 52 patients with biopsy-proven familial amyloidosis born in North America were examined at the Mayo Clinic. At the time of diagnosis of familial amyloidosis, 83% of these patients had peripheral neuropathy, 33% had autonomic neuropathy, and 27% had cardiomyopathy. Renal disease was noted in fewer than 10%, and liver involvement was rare. The median age at diagnosis was 64 years. The...
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