Article
Lethal interaction between heat and methylene blue in Escherichia coli.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group - 1 Jan 2000
Menezes S, Teixeira P
Abstract excerpt
Hyperthermia treatment is shown to act synergistically with methylene blue (MB), from the end point of lethality in Gram-negative Escherichia coli bacteria. That this lethality is correlated to the damage produced in DNA by the dye is deduced from the fact that bacteria differing in capacity for repair are almost equally sensitive to heat, but differ considerably in sensitivity to concomitant heat and dye...
Topics
- DNA Damage
- DNA Repair
- DNA, Bacterial
- Escherichia coli
- Hot Temperature
- Methylene Blue
- Mutation
- Temperature