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Article

DnaK, DnaJ, and GrpE are required for flagellum synthesis in Escherichia coli.

Journal of bacteriology - 1 Oct 1992

Shi W, Zhou Y, Wild J, Adler J, Gross C A

Abstract excerpt

The DnaK, DnaJ, and GrpE heat shock proteins are required for motility of Escherichia coli. Cells deleted for dnaK or dnaJ, or with some mutations in the dnaK or grpE gene, are nonmotile, lack flagella, exhibit a 10- to 20-fold decrease in the rate of synthesis of flagellin, and show reduced rates of transcription of both the flhD master operon (encoding FlhD and FlhC) and the fliA operon (encoding sigma F)....

Topics

Bacterial Proteins
Cell Movement
Escherichia coli
Escherichia coli Proteins
Flagella
Flagellin
Genes, Regulator
HSP40 Heat-Shock Proteins
HSP70 Heat-Shock Proteins
Heat-Shock Proteins
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Recombinant Fusion Proteins

Transcription, Genetic

Source

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Identifiers

PMID: 1400176
DOI: 10.1128/jb.174.19.6256-6263.1992
PMCID: PMC207695

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1400176-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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DnaK, DnaJ, and GrpE are required for flagellum synthesis in Escherichia coli.PMID 1400176Read ↗

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Effect of the arcA mutation on the expression of flagella genes in Escherichia coli.Semantic proximity Read ↗

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Decrease in expression of the master operon of flagellin synthesis in a dnaA46 mutant of Escherichia coli.Semantic proximity Read ↗

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Mutations in flk, flgG, flhA, and flhE that affect the flagellar type III secretion specificity switch in Salmonella enterica.Semantic proximity Read ↗

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